The series of special raw materials for Baorui molecular diagnostic freeze-dried reagents are here!

In recent years, with the continuous development of molecular diagnostic techniques, especially the emergence of POCT rapid detection methods, the requirements for the stability of molecular diagnostic reagents during storage and transportation at room temperature have become increasingly high. For more convenient and safe storage and transportation, freeze-drying liquid reagents is a very good choice. Its advantages include the ability to be transported and stored at room temperature, a longer shelf life, and more flexible sample volume. The optimized freeze-drying formula can ensure the stability of enzymes in the freeze-dried state, and at the same time guarantee that the performance of freeze-dried preparations is not affected after rapid hydration and activation.

Since 2014, Baorui Biology hasWe are engaged in the development of dedicated raw materials for freeze-drying molecular diagnostic reagents. Currently, we have a complete set of dedicated raw materials for freeze-drying suitable for fluorescence quantitative detection of DNA and RNA, including numerous series of dedicated raw material products such as enzymes for freeze-drying, premix solutions, freeze-drying protectants, rapid amplification and direct amplification reagents for freeze-drying, and Lamp isothermal amplification reagents for freeze-drying.

The above-mentioned freeze-drying dedicated raw materials have undergone extensive long-term accelerated stability verification, which can provide more powerful support for the research and development of freeze-drying reagents. After long-term practical exploration, Baorui Biology offers you a set of efficient pre-project solutions for the freeze-drying project of molecular diagnostic reagents

In the early stage of the project, Baorui Biotechnology and the client jointly explored the feasibility of the project, providing a complete set of freeze-drying PCR raw materials, freeze-drying protectants, freeze-drying procedures, etc. The client only needed to provide the relevant primers and probes for the project to explore the feasibility of the project. Baorui Biology also undertakes small-batch freeze-drying services. The freeze-drying forms available for customers to choose from include spherical freeze-drying, vial freeze-drying and conventional eight-tube freeze-drying, helping customers quickly obtain reliable project exploration results.

Borui can freeze-dry PCR detection raw materialsFeatures

All PCR testing raw materials support freeze-drying formulas

Eight-tube, freeze-dried microspheres, vials

The stability verification is thorough, the products are diverse, and there are certified customers.

I. Stability Data of eight-tube freeze-drying

Accelerate for 150 days at 37℃ ▼

45℃ acceleration for 60 days ▼

Note: The control group was immediately prepared with the same batch of liquid reagents as the freeze-dried reagents. After the freeze-dried reagents were taken out of the box, they were vacuum-packed in aluminum foil bags and accelerated at 37/45℃.

02

RNAFreeze-dried amplification reagent products

Test: Triple detection system for total human RNA

Accelerated stability(37℃)Verification

Experimental conditions:

Note: The control group was prepared immediately with the same batch of liquid reagents as the freeze-dried reagents. After the freeze-dried reagents were taken out of the box, they were vacuum-packed in aluminum foil bags and accelerated at 37℃.

Experimental results:

Accelerate for 150 days at 37℃ ▼

03

LAMP isothermal amplification reagent freeze-dried product

Test 1: λDNA detection of DNA-LAMP freeze-dried system

Verification of accelerated stability (accelerated at 55℃ for 30 days)

Experimental conditions:

Note: The control group was immediately prepared with the same batch of liquid reagents as the freeze-dried reagents. After the freeze-dried reagents were taken out of the box, they were vacuum-packed in aluminum foil bags and accelerated at 55℃.

Experimental results:

Accelerate for 30 days at 55℃ ▼

Test TwoHuman total RNA detection RT-LAMP freeze-dried system

Verification of accelerated stability (accelerated at 55℃ for 12 days)

Experimental conditions:

Note: The control group was immediately prepared with the same batch of liquid reagents as the freeze-dried reagents. After the freeze-dried reagents were taken out of the box, they were vacuum-packed in aluminum foil bags and accelerated at 55℃.

Experimental results:

Accelerate at 55℃ for 12 days ▼

Ii. Freeze-drying stability Data of vials

RNAFreeze-dried amplification reagent products

Test: Triple detection system for total human RNA

Accelerated stability(55℃)Verification

Experimental conditions:

NoteThe control group was immediately prepared with the same batch of liquid reagents as the freeze-dried reagents. After the freeze-dried reagents were taken out of the box, they were sealed with a cap and accelerated at 55℃.

Experimental results:

55℃ acceleration for 14 days ▼

Iii. Spherical Freeze-drying Stability Data

The freeze-dried reagent series products of Baorui Biology have been recognized by many customers for their customized services and stable and outstanding product performance. They have been widely applied in the product development process of customers. Currently, some customers' freeze-dried reagent products have been the first to obtain NMPA registration approval.

Trial application

Business Contact: Mr. Liu

Telephone: 186-6692-6804

Email: liuxinyuan@biori.com.cn