RNase R

RNase R (Ribonuclease R) is derived from the RNR superfamily of Escherichia coli and is dependent on Mg²The exonuclease of + completely hydrolyzes linear RNA into dinucleotides and trinucleotides from the 3'→5' direction. It is not sensitive to circular RNA and double-stranded RNA and can be used in the production of special structure Rnas, such as circular RNA (circRNA), lasso structure RNA (lariat RNA), double-stranded RNA with a 3' protruding end of less than 7 nucleotides, and tRNA with complex structures, etc. RNase R is often used in gene expression and alternative splicing studies. It can digest linear RNA to enrich circ RNA or lariat RNA.

Product item Number: BP-E08

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