rcAAV-2/N Detection Kit (PCR-Fluorescence Probe Method)

This kit is based on the fluorescence quantitative PCR method. Primer probes are designed specifically for the GALV gene and are paired with ready-to-use quantitative reference materials.withFor quantitative detection of retrovirusesReplicable retrovirus RCR in cell therapy products and gene therapy products produced from vectors.Used in conjunction with the Baorui Biological Nucleic Acid Extraction or Purification Kit II (Magnetic Bead Method)withThe entire test can be completed in as fast as 120 minutes.

Adeno-associated virus (AAV) is currently widely usedwithThe gene therapy vector belongs to the parvovirus family. Recombinant adeno-associated virus (rAAV) is in the wildrawA gene vector modified on the basis of type AAV. Replicating adeno-associated virus (rcAAV) is present in rAAV vectorsrawDuring the production process, it developsrawNon-homologous recombination formed AAV with replication ability, namely rcAAV. The National Medical Products Administration pointed out that quality control of rcAAV is necessary in gene therapy products. This kit adoptswithThe PCR-fluorescence probe method, the kit contains two systems for detecting rcAAV and rAAV; The kit can simultaneously achieve rapid, sensitive and specific quantitative detection of rcAAV and rAAV.

This kit, when used in conjunction with the Baorui Biological Nucleic Acid Extraction or Purification Kit (magnetic bead method), can quantitatively detect rcAAV as low as 20copies/μL within as little as 1.5 hours.

This kit has undergone comprehensive methodological validation in accordance with relevant regulations, guidelines and other document requirements, and can provide performance validation reports.

Product item number：BP-QN28-100

Product advantages

//cdn.myxypt.com/05aa6382/24/06/c70d6384b78260c1a8780e06d007f0e3786cdb8f.png